Gay by nature: Part one – Dr Qazi Rahman of Queen Mary University London

April 17, 2012 at 9:29 pm (Health, Phychology, Sicence)

Dr Qazi Rahman of Queen Mary University London
Dr Qazi Rahman of Queen Mary University London

What causes homosexuality? Can sexual orientation be changed? And are the brains of gay people different from those of straight people? Adrian Tippetts meets Dr Qazi Rahman, an assistant professor in Cognitive Biology from Queen Mary University London, to find out more.

While almost all scientists accept homosexuality has purely natural causes, the debate has been mired in confusion. There have been conflicting reports about the existence of ‘gay’ genes and their significance. Religious propagandists have tried to promote the myths that sexuality is changeable. And the mainstream media, more interested in causing controversy than holding rational debate, has done little to raise public understanding about the issue. For Dr Rahman, who heads QMUL’s Biological and Experimental Psychology Group, it is quite clear: you’re born gay, and that’s that.

I begin by asking him what aspects of biology are responsible for sexual orientation.

“The whole nature-nurture debate is entirely pointless,” he says. “Sexual orientation is not a choice because humans come in two types: one with a vagina, the other with a penis, so sexual orientation is entirely biological.

“We all end up at the same point: heterosexuality or homosexuality. There is little variation in between but this is not to exclude bisexual behaviour. People do not end up sexually attracted to bananas or animals for example. This is not a flippant comment. What I am saying is that we see the same characteristic traits and behaviours, resulting from a relatively small number of factors.

“We think the causes for different sexual orientations cluster around two areas. We know that just under half the variation in sexual orientation is down to genes. Then the rest of the variation is down to ‘non-shared’ factors, and those, like hormones, are primarily biological.”

At this point a little background is needed.

Dr Rahman explained that the gene story originated in 1993, when geneticist Dean Hamer published a study that claimed homosexuality was genetically influenced, and pinpointed the stretch of the X chromosome (inherited from the mother). He studied 76 pairs of gay brothers and found they shared a stretch of DNA. However, since then no research has been able to repeat the test.

Despite the shortcomings of Hamer’s research, scientists agree the environmental factors do not cause homosexuality. It is increasingly clear that no single gene is responsible for sexual orientation. Furthermore, William Reiner at the University of Oklahoma surveyed the sexuality of a group who had been surgically reassigned from boys to girls at birth, due to genital deformities. Though they were brought up as women, and knew nothing about their surgery, they were all attracted to women later in life.

Michael Bailey of Northwestern University found that an identical twin of a gay man had a 50 per cent chance of also being gay. Among fraternal, yet non-identical twins, that probability was reduced to 20 per cent. This latter statistic does not in fact downplay the role of genetics, because not all the genes we inherit are active. We receive two alternative genes of every gene – one from each parent. Our bodies, therefore, contain two sets of building plans. A process called methylation turns off certain genes, and determines whether the gene we inherit from the mother or the father gets turned on. Although this process is inherited, it has none of DNA’s proof-reading mechanisms, and thus varies greatly from one generation to the next. The causes and effects of methylation are under investigation by Sven Bocklandt at UCLA.

But if homosexuality were inherited, wouldn’t the genes for it disappear because of natural selection?

Dr Rahman said: “That is a common misunderstanding, and that is said by people with no understanding of evolutionary biology. Sexuality is a complex human trait, just like IQ or personality. It is determined not by a single gene, but how several genes work together. A whole range of features with reproductive disadvantages can be maintained in the gene pool down the generations, if only a portion of the genes responsible are advantageous to heterosexual carriers.”

He continued: “One of the ideas is that heterosexual men that may carry some ‘gay’ alleles that result in more empathic and nurturing traits, which are thus more attractive to females, who might mate with them and then carry those genes on further. So long as passing on some versions of those genes is reproductively advantageous, the fact that at some point down the generations you end up with a completely homosexual male – with all gay genes activated – is inconsequential. Evolution will happily tolerate that as long as the general reproductive advantage for individuals is maintained.

“However,” he added, “there is much work to do. We don’t yet know how this works. A couple of papers published last year suggested females, rather than males, benefited. Genes responsible for homosexuality have to do something, but they do not literally write the word ‘gay’ in the brain.

“Maybe they are involved in producing certain types of proteins or hormones which confer attraction to males, useful for women, but maybe having some of these alleles make them more attractive to men, or maybe these genes make them look more beautiful, effeminising them in some way.

“Either way, these help females find a mate more easily and give them more offspring, while almost sterilising the male line. A male who is gay won’t compete with your own reproductive outcomes. At the genomic level, females should be more interested in producing ‘like’ i.e., more females.”

The second influence on sexuality is hormones.

Dr Rahman continued: “The level of exposure to sex hormones, such as testosterone, during life in the womb, seems to influence the direction of sexual preference. Everyone would be born female if it were not for testosterone. At stages during pregnancy, the hormone is introduced into the womb. The level of testosterone to which the foetus is exposed determines the level of masculinity. Some bodily markers provide an insight into exposure. One example is the relative length of index finger to ring finger.

“There are a whole range of measures like startle responses, a particular sound emission that comes from the inner ear and cognitive profiles, which show how people perform on different problem solving tasks.”

So, gay brains are wired differently?

“In males the big brother effect is also important. Gay men tend to be born younger in relation to their brothers. The maternal immune system recognises successive male foetuses and may form an immune response to particular types of protein that form on the surface of the brain in the developing foetus. This might affect sexual differentiation or it might produce some hormonal mechanism that produces that variation, too. The big brother effect only appears to be important when gay men are right handed. Left handed gay men owe their sexual orientation to other causes we are unaware of.

“Relatively recently, there has been lots of research into neurobiology – what goes on in the brain. Our lab has been working a lot on mental problem solving skills like spatial ability, finding your way around, finding important objects in a spatial environment, emotional skills and verbal recognition.

“And we know these are different between the sexes, but we find gay men tend to have a female type of spatial ability. Spatial ability is controlled partly by two regions of the brain. So if we know that gay men perform differently in these kinds of tests, that suggests that part of the brain either is structurally different or functions in a different way. That gives us an insight into brain development.

“Thanks to MRI scans, we also have the technology to look at the brain directly rather than just carry out problem solving tests on people. The studies in the last two years strongly suggest that in the adult gay brain, and lesbian brain, it is wired very differently to the straight brain.

“In 2008, Swedish scientists at the Karolinska Institute compared the brain hemispheres of healthy gays and lesbians with heterosexual male and female adults.

“The results showed that heterosexual men and lesbians show a rightward asymmetry in their brain – it appears to be larger in volume than the left. However, the brain hemispheres of gay men and heterosexual women were more symmetrical.

“It might explain why heterosexual men tend to be better at spatial skills; there is some evidence that lesbians are better at some visual motor skills as well. Tests show gay men and hetero women tend to be better at language, verbal fluency, skills and emotion processing.

“The Swedish group also found differences in the amygdala, the part of the brain responsible for orientating the rest of the brain in response to an emotional stimulus, such as a startle (fight or flight) response, or the presence of a potential mate.

“Heterosexual men and gay women have more nerve connections in the right side of the amygdala, while gay men and heterosexual women have more on the left.

“So, the brain network which determines what sexual orientation actually ‘orients’ towards is similar between gay men and straight women, and between gay women and straight men.”

Now some may ask ‘but how can you be sure that having gay sexual experiences or straight sexual experiences is not responsible for these differences and surely experience can change brain structure?’

Dr Rahman says this is a good question: “We don’t know the answer but studies with animals suggest these differences appear before any sexual experiences calibrate the biology. But only work in humans can truly answer this, and this remains to be done.”

So does the data justify stereotypes? Does it suggest footballers and athletes are less likely to be gay? And could research uncover why some people are homophobic?

Permalink Leave a Comment

Teen Suicide Awareness: Statistics

March 15, 2012 at 2:16 am (General Information, Health, Phychology)

How real is the problem of youth suicide? Here are the numbers:

  • EVERY YEAR there are approximately 10 youth suicides for every 100,000 youth.
  • EVERY DAY there are approximately 11 youth suicides.
  • EVERY 2 HOURS AND 11 MINUTES a person under the age of 25 completes suicide

 

How pervasive is the problem of youth suicide? Here’s a brief review of what national data tell us:

  • Suicide is the third leading cause of death for teens.
  • Suicide is second leading cause of death in colleges.
  • For every suicide completion, there are between 50 and 200 attempts.
  • CDC Youth Risk Survey: 8.5% of students in grades 9-12 reported a suicide attempt in the past year.
  • 25% of high-school students report suicide ideation.
  • The suicide attempt rate is increasing for youths ages 10-14.
  • Suicide had the same risk and protective factors as other problem behaviors, such as drugs, violence, and risky sexual activities.
  • While a single suicide is a tragedy, it is estimated that for every adolescent who completes suicide, there are between 50 and 200 suicide attempts.
  • A recent survey of high-school students found that almost 1 in 5 had seriously considered suicide; more than 1 in 6 had made plans to attempt suicide; and more than 1 in 12 had made a suicide attempt in the past year.

REF: http://www.teachervision.fen.com/education-and-social-issues/mental-health/57131.html

Permalink Leave a Comment

THE HEALTH OF LGBT

January 11, 2012 at 9:36 pm (Health)

About LGBT Health

People who are lesbian, gay, bisexual, or transgender (LGBT) are members of every community. They are diverse, come from all walks of life, and include people of all races and ethnicities, all ages, all socioeconomic statuses, and from all parts of the country. The perspectives and needs of LGBT people should be routinely considered in public health efforts to improve the overall health of every person and eliminate health disparities.

In addition to considering the needs of LGBT people in programs designed to improve the health of entire communities, there is also a need for culturally competent medical care and prevention services that are specific to this population. Social inequality is often associated with poorer health status, and sexual orientation has been associated with multiple health threats. Members of the LGBT community are at increased risk for a number of health threats when compared to their heterosexual peers [1-5]. Differences in sexual behavior account for some of these disparities, but others are associated with social and structural inequities, such as the stigma and discrimination that LGBT populations experience.

These pages provide information and resources on some of the health issues and inequities affecting LGBT communities. Links to other information sources and resources are also provided. Some of this information is designed for members of the general public. Other information has been developed for health care providers, public health professionals, and public health students.

 

Sexually Transmitted Diseases

pastedGraphic.pdf

Key STD Resources

 

  • Syphilis Resources
  • HPV Resources

 

 

Consistent and Correct Use of Condoms

To achieve maximum protection by using condoms, they must be used consistently and correctly.

The failure of condoms to protect against STD/HIV transmission usually results from inconsistent or incorrect use, rather than product failure.

 

Sexually Transmitted Diseases (STDs) have been increasing among gay and bisexual men. Recent increases in syphilis cases have been documented across the country. In 2008, men who have sex with men (MSM) accounted for 63% of primary and secondary syphilis cases in the United States. MSM often are diagnosed with other bacterial STDs, including chlamydia and gonorrhea infections.

Gay and bisexual men can be infected with HPV (Human Papillomavirus), the most common STD in the United States. Some types of HPV cause genital and anal warts and some can lead to the development of anal and oral cancer. Men who have sex with men are 17 times more likely to develop anal cancer than heterosexual men. Men who are HIV-positive are even more likely than those who are uninfected to develop anal cancer. See Primary and Secondary Syphilis—Reported Cases, 2008, by Sexual Orientation.

How are STDs spread?

  • Gonorrhea and chlamydia are sexually transmitted by genital secretions, such as urethral secretions from the penis
  • Genital herpes and syphilis are transmitted primarily through skin-to-skin contact with sores/ulcers or infected skin that looks normal
  • HPV is transmitted through contact with infected genital skin or mucosal surfaces/secretions, such as the penis and anus

What are the signs and symptoms of STDs?

Some STDs do not cause any symptoms, while others can cause various symptoms, including:

 

  • A discharge from your penis.
  • Pain, burning, or itching around the opening of your penis when you urinate.
  • Anal itching, soreness, and bleeding, or discharge.
  • A single sore or multiple sores on the penis.
  • Rash on the palms of the hands or bottom of feet.
  • Painful blisters around the genitals or anus.
  • Warts on the genital area, including the penis and scrotum.

When should I be tested?

All gay, bisexual, and other MSM should be tested each year for STDs (including HIV). Always see a doctor if you have any signs and symptoms of an STD. It is important to get tested so you can get the needed medications to cure the infection or alleviate its symptoms. Be sure to tell your recent sex partners, so they can get tested too. Talk openly and honestly with your partner about STDs. It is also essential that you avoid having sex until you and your partner have both finished your treatment, so you don’t re-infect each other.

How can I prevent STDs?

The most reliable ways to avoid transmission of STDs are to abstain from sexual activity, or to be in a long-term mutually monogamous relationship with an uninfected partner. Consistent and correct use of male latex condoms reduces the risk of STD transmission. However, condom use cannot provide absolute protection against any STD. There is also a vaccine available to prevent HPV in females and males.

Can STDs Be Treated?

Antibiotics can successfully cure bacterial STDs, including chlamydia, gonorrhea, and syphilis. However, drug-resistant strains of gonorrhea are increasing in many areas of the world, including the United States, and successful treatment of gonorrhea is becoming more difficult.

There is no treatment that can cure viral STDs, such as HPV and genital herpes. Antiviral medications can shorten and prevent herpes outbreaks during the period of time the person takes the medication. In addition, daily suppressive therapy for symptomatic herpes can reduce transmission to partners. Visible warts caused by HPV can be treated and removed.

Youth

pastedGraphic_2.pdf

Many lesbian, gay, bisexual, and transgender (LGBT) youth are happy and thrive during their adolescent years. Going to a school that creates a safe and supportive learning environment for all students and having caring and accepting parents are especially important. This helps all youth achieve good grades and maintain good mental and physical health. However, some LGBT youth are more likely than their heterosexual peers to experience difficulties in their lives and school environments, such as violence.

Experiences with Violence

Negative attitudes toward gays, lesbians, bisexuals, and transgender people put LGBT youth at increased risk for experiences with violence, compared with other students [1]. Violence can include behaviors such as bullying, teasing, harassment, physical assault, and suicide-related behaviors.

 

How CDC Promotes Health Safety Among Youth – Read LGBTQ Youth Programs-At-A-Glance

 

A 2009 survey* of more than 7,000 LGBT middle and high school students aged 13–21 years found that in the past year, because of their sexual orientation—

  • Eight of ten students had been verbally harassed at school;
  • Four of ten had been physically harassed at school;
  • Six of ten felt unsafe at school; and
  • One of five had been the victim of a physical assault at school [2].

*Survey participants were recruited online and through community-based groups and service organizations serving LGBT youth.

Bullying and LGBT Youth

 

pastedGraphic_3.pdf

President Obama addresses bullying among LGBT Youth.

pastedGraphic_4.pdf

White House staff add their voices to the project, It Gets Better.

pastedGraphic_5.pdf

Secretary Sebelius’s message to LGBT youth experiencing bullying and intolerance.

LGBT youth are also at increased risk for suicidal thoughts and behaviors, suicide attempts, and suicide. A nationally representative study of adolescents in grades 7–12 found that lesbian, gay, and bisexual youth were more than twice as likely to have attempted suicide as their heterosexual peers [3]. More studies are needed to better understand the risks for suicide among transgender youth.

Another survey of more than 7,000 seventh- and eighth-grade students from a large Midwestern county examined the effects of school climate and homophobic bullying on lesbian, gay, bisexual, and questioning (LGBQ) youth and found that

  • LGBQ youth were more likely than heterosexual youth to report high levels of bullying and substance use;
  • Students who were questioning their sexual orientation reported more bullying, homophobic victimization, unexcused absences from school, drug use, feelings of depression, and suicidal behaviors than either heterosexual or LGB students;
  • LGB students who did not experience homophobic teasing reported the lowest levels of depression and suicidal feelings of all student groups (heterosexual, LGB, and questioning students); and
  • All students, regardless of sexual orientation, reported the lowest levels of depression, suicidal feelings, alcohol and marijuana use, and unexcused absences from school when they were
    • In a positive school climate and
    • Not experiencing homophobic teasing [4].

More resources for LGBT youth and their friends

Effects on Education and Health

Exposure to violence can have negative effects on the education and health of LGBT youth. In a national study of middle and high school students, LGBT students (61.1%) were more likely than their non-LGBT peers to feel unsafe or uncomfortable as a result of their sexual orientation. LGBT students (over 25%) reported missing classes or days of school because of feeling unsafe in their school environment [2].

Overall, the stresses experienced by LGBT youth also put them at greater risk for mental health problems, substance use, and physical health problems [1].

What Schools Can Do

For youth to thrive in their schools and communities, they need to feel socially, emotionally, and physically safe and supported. A positive school climate has been associated with decreased depression, suicidal feelings, substance use, and unexcused school absences among LBGT students [5,6].

School personnel, leaders of community organizations, parents, and youth have a role to play in building positive, supportive, and healthy environments for youth. Such environments promote acceptance and respect and help youth feel valued [7]. Schools can assist by implementing clear policies, procedures, and activities designed to prevent violence. For example, a study, found that, in schools with LGB support groups (such as gay-straight alliances), LGB students were less likely to experience threats of violence, miss school because they felt unsafe, or attempt suicide than those students in schools without LGB support groups [8].

To help promote health and safety among LGBTQ youth, schools can implement the following policies and practices:

  • Encourage respect for all students and prohibit bullying, harassment, and violence against all students.
  • Identify “safe spaces,” such as counselors’ offices, designated classrooms, or student organizations, where LGBTQ youth can receive support from administrators, teachers, or other school staff.
  • Encourage student-led and student-organized school clubs that promote a safe, welcoming, and accepting school environment (e.g., gay-straight alliances, which are school clubs open to youth of all sexual orientations).
  • Ensure that health curricula or educational materials include HIV, other STD, or pregnancy prevention information that is relevant to LGBTQ youth; such as, ensuring that curricula or materials use inclusive language or terminology.
  • Encourage school district and school staff to develop and publicize trainings on how to create safe and supportive school environments for all students, regardless of sexual orientation or gender identity and encourage staff to attend these trainings.
  • Facilitate access to community-based providers who have experience providing health services, including HIV/STD testing and counseling, to LGBTQ youth.
  • Facilitate access to community-based providers who have experience in providing social and psychological services to LGBTQ youth.

More resources for educators and school administrators

What Parents Can Do

Parents should talk openly with their children about any problems or concerns and be watchful of behaviors that might indicate their children are victims or perpetrators of bullying or violence or are depressed or suicidal. If bullying, violence, or depression is suspected, parents should take immediate action, working with school personnel and other adults in the community.

Also, how parents respond to their LGBTQ child can have a tremendous impact on their child’s current and future mental and physical health [1,6,9,10]. Supportive reactions can help youth cope with the challenges of being an LGBTQ teen. However, some parents react negatively to learning that they may have an LGBTQ daughter or son. In some cases, children are thrown out of the house or stress and conflict at home can cause some youth to run away. As a result, LGBT youth are at greater risk for homelessness than their heterosexual peers [1].

Even less severe reactions can have long-lasting negative effects. Research published in the journal Pediatrics found significantly higher rates of mental and physical health problems among LGBT young adults who experienced high levels of rejection from their parents while they were adolescents [9]. Compared with LGBT young adults who experienced very little or no parental rejection, LGBT young adults who experienced high levels of rejection were

  • Nearly 6 times as likely to have high levels of depression;
  • More than 8 times as likely to have attempted suicide;
  • More than 3 times as likely to use illegal drugs; and
  • More than 3 times as likely to engage in unprotected sexual behaviors that put them at increased risk for HIV and other sexually transmitted infections.

The resources provided below can help parents better understand and respond to the needs of LGBTQ adolescents.

Preview of “Ten Tips for Parents of a Gay, Lesbian, Bisexual, or Transgender Child”

health risks of gay sex SSA

wsw

Top Ten Trans

Top Ten Lesbians

talking

bp-prevention

Standards of Care V7 – 2011 WPATH

Are Parents and Teens Talking about Sex

lgbt

English_Final_Print_Version_Last

Fenway_bisexual_safe_sex_brochure_NEW

Characteristics of Parents of Sexually Healthy Adolescents

 

Permalink Leave a Comment

GLOBAL REPORT UNAIDS REPORT ON THE GLOBAL AIDS EPIDEMIC – 2010

January 11, 2012 at 8:36 pm (Health)

20101123_GlobalReport_full_en

20101123_2010_HIV_Prevalence_Map_em

Permalink Leave a Comment